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Genomic Science Program

Today, scientists have in hand the complete DNA sequences of genomes for many organisms—from microbes to plants to humans. The U.S. Department of Energy's Genomic Science program (formerly Genomics:GTL) uses microbial and plant genomic data, high-throughput analytical technologies, and modeling and simulation to develop a predictive understanding of biological systems behavior relevant to solving energy and environmental challenges including bioenergy production, environmental remediation, and climate stabilization. Learn More »
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Biofuels

Alternative fuels from renewable cellulosic biomass are expected to significantly reduce U.S. dependence on imported oil while enhancing national energy security and decreasing the environmental impacts of energy use. Developing a cost-effective, commercial-scale cellulosic biofuel industry will require transformational biological research in feedstock development, biomass deconstruction, and fuel synthesis. Learn More »


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Knowledgebase

Driven by the ever-increasing wealth of data resulting from new generations of genomics-based technologies, systems biology is demanding a computational environment for comparing and integrating large, heterogeneous datasets and using this information to develop predictive models. To address this challenge, the Genomic Science program is developing the DOE Systems Biology Knowledgebase. Learn More »


Click to learn more about carbon cycling and the climate.

Carbon Cycling and Climate

The global carbon cycle plays a central role in regulating atmospheric carbon dioxide levels and thus Earth’s climate, but our basic understanding of the tightly interlinked biological processes driving the carbon cycle remains limited. Advancing our knowledge of these processes is crucial to predicting potential climate change impacts, assessing the viability of climate change adaptation and mitigation strategies, and informing relevant policy decisions. Learn More »


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2012 Genomic Science Awardee Meeting X Abstracts


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Applications of New DOE National User Facilities in Biology report


Biosystems Design: Report from the July 2011 Workshop


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Genomic Science-Related BER Research Highlights

  • Switchgrass Sequencing Provides Insight into Genome Structure and Organization [Apr 12, 2012]
    Perennial switchgrass (Panicum virgatum L.) is capable of producing high biomass yields wi [more...]
  • Understanding How Bacteria Use Sunlight [Apr 05, 2012]
    Cyanobacteria are prime candidates for the biological production of biofuels, especially hydrogen [more...]
  • Using Systems Biology to Understand Complex Microbial Communities [Mar 27, 2012]
    The ability to effectively model and predict integrated functional properties across complex grou [more...]
  • Microbes Stress Out During Conversion of Pretreated Biomass to Biofuels [Mar 02, 2012]
    Chemical pretreatment of plant biomass prior to enzymatic breakdown significantly improves the re [more...]
  • Using High-Performance Computing to Study the Hydration of Cellobiose [Feb 16, 2012]
    Cellobiose, the two glucose basic repeat unit of cellulose, is formed during enzymatic or acidic [more...]
  • More BER Research Highlights »