Science Focus Area: Pacific Northwest National Laboratory
- Principal Investigators: Kirsten S. Hofmockel1
- Laboratory Research Manager: Brian Thrall1
- Co-Investigators: Janet K. Jansson1, Ryan McClure1, Christopher Anderton1, Mary Lipton1, Tom Metz1, Michelle Davison1, Jason McDermott1, Nikos Kyrpides2, Ari Jumpponen3, Hyun-Seob Song4, Steven Fransen5
- Unfunded Collaborators: Leslie Shor6
- Participating Institutions: 1Pacific Northwest National Laboratory, 2U.S. Department of Energy Joint Genome Institute, 3Kansas State University, 4University of Nebraska–Lincoln, 5Washington State University, 6University of Connecticut
- Project Website: pnnl.gov/projects/soil-microbiome-science-focus-area
- Overview Brochure: Download PDF
- KBase Collaboration: Metabolic network reconstruction of microorganisms and communities
Summary

Soil Microbiome. The Soil Microbiome SFA, led by Pacific Northwest National Laboratory, studies how changes in soil moisture influence the soil microbiome and metaphenome. The SFA team uses a variety of genome-enabled modeling approaches to determine reaction networks, interaction networks, and interkingdom interactions. [Reused under a Creative Commons license (CC BY 4.0) from Jansson, J. K. and K. S Hofmockel. 2018. “The Soil Microbiome — From Metagenomics to Metaphenomics,” Current Opinion in Microbiology 43, 162–68. DOI: 10.1016/j.mib.2018.01.013.]