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Genomic Science Program

Systems Biology for Energy and the Environment

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Genomic Science Program

2015 Awardee

Parallel analysis of Puccinia emaculata virulence and switchgrass resistance phenotypes

INVESTIGATORS: Shavannor Smith (PI), Jeffrey L. Bennetzen, Katrien M. Devos

INSTITUTIONS: University of Georgia Athens

PROJECT SUMMARY: The classic approach to the study of the genetic basis of plant disease resistance has led to a great deal of crop improvement, especially in species like wheat where rust diseases are the major biotic limitation on food production. However, this genetic analysis, as pioneered by Flor, Hooker and Saxena and others, requires significant expertise in both plant pathology and genetics. Moreover, the establishment of a differential host series to distinguish pathogen races, and the collection/testing of pathogen isolates to allow the discovery and isolation of a spectrum of races, has traditionally been a multi-year undertaking. In the genomics era, if one can find a way to analyze a trait by DNA sequence analysis, then it is likely to be quicker, more definitive and more comprehensive than any other approach. Hence, one of the goals of this proposed project is to develop a new approach for characterization of field isolates of P. emaculata, where we combine classical and molecular methods to identify host resistance genes and pathogen avirulence loci, then use the gained knowledge to develop DNA sequence tools that will allow immediate field diagnostics.  Our goals are to create a resource of specific P. emaculata races, to identify specific switchgrass resistance genes that act against these specific P. emaculata races, to discover candidate effector genes in the pathogen that interact with specific switchgrass resistance genes, and to develop and to test our models of these interactions on switchgrass cultivars infected with field rust isolates.

Name: Smith, Shavannor
Phone: 706-542-1280


Genomics-Enabled Plant Biology for Determination of Gene Function Summaries of Projects Awarded by Year

Plant Feedstock Genomics for Bioenergy [01/19]

Lignocellulosic Biomass for Advanced Biofuels and Bioproducts: Workshop Report [2/15]

Sustainable Bioenergy [05/14]

  • New Funding Announcement: DE-FOA-0002214 - Systems Biology Research To Advance Sustainable Bioenergy Crop Development
    Additional Information » [01/20]
  • New Funding Announcement: DE-FOA-0002215 - ESPCoR FOA 2215 Building EPSCOR-State/National Laboratory Partnerships
    Additional Information » [12/19]
  • New Funding Announcement: DE-FOA-0002217 – Computational Tool Development for Integrative Systems Biology Data Analysis Additional Information » [11/19]
  • New Funding Announcement: DE-FOA-0002173 – Early Career Research Program Additional Information » [11/19]
  • Now Available: Breaking the Bottleneck of Genomes: Understanding Gene Function Across Taxa report [9/19]
  • 2019 PI Meeting: Genomic Sciences Program Annual Principal Investigator Meeting February 24 - 27, 2019. Abstracts and More »
  • DOE Announces $64 Million for Plant and Microbe Research: U.S. Department of Energy announced $64 million in funding for 25 university-led genomics research projects on plants and microbes for bioenergy and bioproducts. [8/19]
    Read More »
  • $13.5 Million for New Bioimaging Approaches for Bioenergy: The U.S. Department of Energy announced $13.5 million in funding for six projects to develop new approaches to microscopic imaging of plants and microbes. [8/19]
    Read More »
  • More News and Announcements »

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