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Genomic Science Program

Systems Biology for Energy and the Environment

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Genomic Science Program

2014 Awardee

Coordinated Genetic Improvement of Bioenergy Sorghum for Compositional and Agronomic Traits

INVESTIGATORS: Patrick Brown (PI), Markus Pauly

INSTITUTIONS: University of Illinois Urbana-Champaign, University of California Berkeley

PROJECT SUMMARY:The goal of this project is to discover and characterize novel genetic variants that affect lignocellulosic composition and saccharification yield in bioenergy feedstock grasses without compromising agronomic performance. Sorghum is a stress- tolerant C4 grass that performs well under drought, flooding, extreme heat, and salinity. Photoperiod-sensitive sorghum varieties accumulate large quantities of vegetative biomass suitable for bioenergy production. Variation in maturity is usually a major source of confounding for marker-trait association studies in diverse germplasm, but is minimal when photoperiod-sensitive sorghums are grown in a temperate environment. Simultaneous evaluation of lignocellulosic compositional and agronomic traits will allow the prioritization of genetic variants that improve overall bioenergy production per unit area. The objectives of the project are: 1) to characterize additive genetic variation in compositional and agronomic traits in a panel of 600 diverse sorghum inbreds; 2) discover genetic variants for these traits using genome-wide association; 3) identify dominance and epistatic effects for these variants in hybrids and F3 families; 4) understand mechanisms of trait variation using detailed compositional and transcriptomic analysis in near-isogenic lines; and 5) use selection indices to translate these results into breeding values tailored to individual conversion platforms. Sorghum is the closest diploid sequenced genome to Saccharum and Miscanthus, two other grass genera that are also promising bioenergy feedstocks. Identification of useful traits and variants in sorghum will thus help guide and accelerate the genetic improvement of both bioenergy sorghum and closely related perennial grasses.

Name: Brown, Patrick
Phone: 217-333-8182


Genomics-Enabled Plant Biology for Determination of Gene Function Summaries of Projects Awarded by Year

Plant Feedstock Genomics for Bioenergy [01/19]

Lignocellulosic Biomass for Advanced Biofuels and Bioproducts: Workshop Report [2/15]

Sustainable Bioenergy [05/14]

  • New Funding Announcement: DE-FOA-0002214 - Systems Biology Research To Advance Sustainable Bioenergy Crop Development
    Additional Information » [01/20]
  • New Funding Announcement: DE-FOA-0002215 - ESPCoR FOA 2215 Building EPSCOR-State/National Laboratory Partnerships
    Additional Information » [12/19]
  • New Funding Announcement: DE-FOA-0002217 – Computational Tool Development for Integrative Systems Biology Data Analysis Additional Information » [11/19]
  • New Funding Announcement: DE-FOA-0002173 – Early Career Research Program Additional Information » [11/19]
  • Now Available: Breaking the Bottleneck of Genomes: Understanding Gene Function Across Taxa report [9/19]
  • 2019 PI Meeting: Genomic Sciences Program Annual Principal Investigator Meeting February 24 - 27, 2019. Abstracts and More »
  • DOE Announces $64 Million for Plant and Microbe Research: U.S. Department of Energy announced $64 million in funding for 25 university-led genomics research projects on plants and microbes for bioenergy and bioproducts. [8/19]
    Read More »
  • $13.5 Million for New Bioimaging Approaches for Bioenergy: The U.S. Department of Energy announced $13.5 million in funding for six projects to develop new approaches to microscopic imaging of plants and microbes. [8/19]
    Read More »
  • More News and Announcements »

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