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Genomic Science Program

Systems Biology for Energy and the Environment

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Genomic Science Program

About the DOE National Microbiome Data Collaborative (NMDC)

Community-Driven Data Science System to Advance Microbiome Research

The Department of Energy’s (DOE) National Microbiome Data Collaborative (NMDC) is developing an open-access framework that facilitates more efficient use of microbiome data for applications in energy, environment, health, and agriculture. Over the past few decades, microbiome data have grown exponentially. However, the sheer amount of data available presents a significant bottleneck for analysis and interpretation.

To tackle this data integration challenge, NMDC leverages DOE’s existing data-science resources and high-performance computing systems. The guiding principles at the initiative’s core are (1) making data findable, accessible, interoperable, and reusable (FAIR); (2) connecting data and compute resources; and (3) community engagement that supports open science and shared ownership.

Capabilities being enabled by NMDC include:

  • Aggregating and viewing both taxonomic and functional profiles of unassembled and assembled metagenome sequence data to gain new insights into microbiome composition and function.
  • Accessing, analyzing, and integrating multiomics datasets (metagenome, metatranscriptome, metaproteome, metabolome, and environmental data) to discover community dynamics, metabolic networks, and other microbe-microbe, microbe-host, and microbe-environment interactions.
  • Accelerating searches through linked data using existing and enhanced ways to describe microbiome datasets, diversifying the sample space and depth for new discoveries.

News

  • New Funding Announcement: DE-FOA-0002217 – Computational Tool Development for Integrative Systems Biology Data Analysis Additional Information » [11/19]
  • New Funding Announcement: DE-FOA-0002173 – Early Career Research Program Additional Information » [11/19]
  • Now Available: Breaking the Bottleneck of Genomes: Understanding Gene Function Across Taxa report [9/19]
  • 2019 PI Meeting: Genomic Sciences Program Annual Principal Investigator Meeting February 24 - 27, 2019, [abstracts and more...]
  • DOE Announces $64 Million for Plant and Microbe Research: U.S. Department of Energy announced $64 million in funding for 25 university-led genomics research projects on plants and microbes for bioenergy and bioproducts. [8/21]
    Read More »
  • $13.5 Million for New Bioimaging Approaches for Bioenergy: The U.S. Department of Energy announced $13.5 million in funding for six projects to develop new approaches to microscopic imaging of plants and microbes. [8/21]
    Read More »
  • More News and Announcements »

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