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Genomic Science Program

DOE Bioenergy Research Centers

Miscanthus (GLBRC)
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Miscanthus [Great Lakes Bioenergy Research Center]

Multiple societal benefits underlie U.S. Department of Energy (DOE) research efforts to support a viable and sustainable domestic nonfood lignocellulosic plant biomass biofuel and bioproducts industry. These benefits include ensuring future energy security, lowering greenhouse gases to mitigate climate impacts, diversifying the range of available biobased products, producing fewer toxic chemicals and byproducts, creating jobs in rural areas, and improving the trade balance.

The resistance of lignocellulose to degradation (called recalcitrance) and lack of efficient methods to convert it to useful products are major impediments to the cost-effective production of fuels and chemicals from plant biomass. Innovation stemming from advanced biotechnology-based research is key to accelerating needed improvements in the sustainable production of lignocellulosic biomass, its deconstruction into sugars and lignin byproducts, and conversion to biofuels beyond ethanol (i.e., advanced biofuels) and bioproducts.

New Bioenergy Research Centers Announced

A new phase in bioproduct and bioenergy research was announced in July 2017 with the establishment of four DOE Bioenergy Research Centers (BRCs), which will provide the scientific breakthroughs for a new generation of sustainable, cost-effective bioproducts and bioenergy.

The centers—each led by a DOE National Laboratory or a top university—are designed to lay the scientific groundwork for a new bio-based economy that promises to yield a range of important new products and fuels derived directly from nonfood biomass. Initial funding for the four centers will total $40 million for FY 2018, with plans for a total of five years of funding. See also DOE Announcement.

The Four Centers

  • Great Lakes Bioenergy Research Center, led by the University of Wisconsin-Madison in partnership with Michigan State University. GLBRC's goal is to develop the science and technological advances to ensure sustainability at each step in the process of creating biofuels and bioproducts from lignocellulose.
  • Center for Bioenergy Innovation, led by Oak Ridge National Laboratory. CBI's goal is to accelerate the domestication of bioenergy crops and targeted consolidated bioprocessing innovations to improve cost efficiencies within the bioenergy supply chain.
  • Joint BioEnergy Institute, led by DOE’s Lawrence Berkeley National Laboratory. JBEI's goal is to broaden and maximize production of economically viable fuels and chemicals from plant biomass to enable biorefinery development.
  • Center for Advanced Bioenergy and Bioproducts Innovation, led by the University of Illinois at Urbana-Champaign. CABBI's goal is to enable the direct production of fuels and chemicals in plants as sustainable biofactories for a range of bioproducts.

Bioenergy Centers Address Key Science Themes

  Sustainability Feedstock Development Deconstruction Conversion
  Sustainability Feedstock Development Deconstruction Conversion
Great Lakes Bioenergy Research Center Conduct long-term studies of producing bioenergy crops on marginal land. Design improved dedicated bioenergy crops. Develop renewable biomass deconstruction and separation strategies. Develop novel biomass conversion microbes.
Center for Bioenergy Innovation Optimize water
and nutrient use in dedicated bioenergy crops.
Create multiomics tools for developing high-yield bioenergy crops. Advance integrated and consolidated thermophilic bioprocessing. Generate drop-in biofuels and bioproducts from biomass and lignin residues.
Joint BioEnergy Institute Study environmental resilience of engineered bioenergy crops. Engineer plants for atom-economical conversion into biofuels and bioproducts. Develop feedstock agnostic biomass deconstruction processes using renewable ionic liquids Develop high-throughput synthetic biology tools and hosts for scalable, atom-economical biofuels and bioproducts.
Center for Advanced Bioenergy and Bioproducts Innovation Integrate economic and environmental analyses for biomass supply. Develop “plants as factories” concept for biofuels and bioproducts. Develop product separation technologies for in planta production. Establish automated biofoundry concept for fuels and bioproducts.

Building on a Legacy

Bioenergy Research Centers 10-Year Retrospective: Breakthroughs and Impacts 2007-2017
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Over 10 years (2007-2017), three Bioenergy Research Centers (BRCs), supported by the Genomic Science program within DOE’s Office of Science Office of Biological and Environmental Research (BER), made significant advances toward this new biobased economy. They produced multiple breakthroughs in the form of deepened understanding of sustainable biomass production practices, targeted reengineering of biomass feedstocks, development of new methods for deconstructing feedstocks, and engineering of microbes for more effective production of a diverse range of biofuels.

In all, these three BRCs produced 2,696 peer-reviewed publications, 619 invention disclosures, 397 patent applications, 199 licenses or options, 101 patents, and 14 company startups (see figure, DOE BRCs, Progress Through the First 10 Years). Through this work, they transferred substantial insight and expertise to industry through cooperation with both large and small companies.

For more on these previous centers, see archive: Bioenergy Research Centers 2007-2017 including this list of peer-reviewed publications.

Bioenergy Reports and Documents

Genomics-Enabled Plant Biology for Determination of Gene Function Summaries of Projects Awarded by Year

Bioenergy Research Centers 10-Year Retrospective: Breakthroughs and Impacts 2007-2017 [09/18]

U.S. DOE Bioenergy Research Centers [02/18]

Plant Feedstock Genomics for Bioenergy [01/18]

Basic Research Opportunities in Genomic Science to Advance the Production of Biofuels and Bioproducts from Plant Biomass White Paper [6/15]

Lignocellulosic Biomass for Advanced Biofuels and Bioproducts: Workshop Report [2/15]


Systems Biology for Bioenergy (Summary of Funded Projects)

Sustainable Bioenergy [05/14]

Biosystems Design Report [04/12]

Switchgrass Research Group: Progress Report [1/12]

Sustainability of Biofuels Future Research Opportunities [4/09]

Biomass to Biofuels Report [07/06]

  • New Funding Announcement: DE-FOA-0002214 - Systems Biology Research To Advance Sustainable Bioenergy Crop Development
    Additional Information » [01/20]
  • New Funding Announcement: DE-FOA-0002215 - ESPCoR FOA 2215 Building EPSCOR-State/National Laboratory Partnerships
    Additional Information » [12/19]
  • New Funding Announcement: DE-FOA-0002217 – Computational Tool Development for Integrative Systems Biology Data Analysis Additional Information » [11/19]
  • New Funding Announcement: DE-FOA-0002173 – Early Career Research Program Additional Information » [11/19]
  • Now Available: Breaking the Bottleneck of Genomes: Understanding Gene Function Across Taxa report [9/19]
  • 2019 PI Meeting: Genomic Sciences Program Annual Principal Investigator Meeting February 24 - 27, 2019. Abstracts and More »
  • DOE Announces $64 Million for Plant and Microbe Research: U.S. Department of Energy announced $64 million in funding for 25 university-led genomics research projects on plants and microbes for bioenergy and bioproducts. [8/19]
    Read More »
  • $13.5 Million for New Bioimaging Approaches for Bioenergy: The U.S. Department of Energy announced $13.5 million in funding for six projects to develop new approaches to microscopic imaging of plants and microbes. [8/19]
    Read More »
  • More News and Announcements »

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