About the DOE Genomic Science Program

Advancing Scientific Discovery through Genomics and Systems Biology

Understanding the instructions for life encoded in the DNA sequence, or genome, of natural systems offers a wealth of potential for advancing biological solutions to many of today’s energy and environmental challenges. To harness this potential, the U.S. Department of Energy (DOE) Genomic Science program supports fundamental research to understand the systems biology of plants and microbes as they respond to and modify their local environments. Systems biology is the holistic, multidisciplinary study of complex interactions that specify the function of an entire biological system—whether single cells or multicellular organisms—synthesizing decades of reductionist studies that identified and characterized individual components.