Genomic Science Program

Genomic Science Program Research Awards

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Rapid Deduction of Stress Response Pathways in Metal/ Radionuclide Reducing Bacteria

Lawrence Berkeley National Laboratory
Adam Arkin, Principal Investigator
$36.6 million over 5 years
Funded: FY2002

Research Partners:

• Sandia National Laboratories
  Anup Singh, Co-Principal Investigator
• Oak Ridge National Laboratory
  Jizhong Zhou, Co-Principal Investigator
• University of California at Berkeley
  Jay Keasling, Co-Principal Investigator
• University of Missouri
  Jud Wall, Co-Principal Investigator
• University of Washington
  David Stahl, Co-Principal Investigator
• Diversa, Inc.
  Martin Keller, Co-Principal Investigator

This team will develop computational models to describe and predict the behavior of gene regulatory networks in microbes in response to the environmental conditions found in waste sites contaminated with metals and radionuclides.

Website

Abstracts

• 2005 Contractor-Grantee Workshop
  • Lawrence Berkeley National Laboratory (PDF, 311 kb)
  • VIMSS Computational Microbiology Core Research on Comparative and Functional Genomics
  • The Virtual Institute of Microbial Stress and Survival (VIMSS): Deduction of Stress Response Pathways in Metal/Radionuclide Reducing Microbes
  • VIMSS Applied Environmental Microbiology Core Research on Stress Response Pathways in Metal-Reducers
  • VIMSS Functional Genomics Core: Analysis of Stress Response Pathways in Metal-Reducin Bacteria
• 2004 Contractor-Grantee Workshop
  • VIMSS Computational Microbiology Core Research on Comparative and Functional Genomics
  • Managing the GTL Project at Lawrence Berkeley National Laboratory
  • VIMSS Applied Environmental Microbiology Core Research on Stress Response Pathways in Metal-Reducers
  • VIMSS Functional Genomics Core: Analysis of Stress Response Pathways in Metal-Reducing Bacteria
• 2003 Contractor-Grantee Workshop
  • Rapid Deduction of Stress Response Pathways in Metal/Radionuclide Reducing Bacteria

Proposal:

• Web or PDF file 4.7 MB

Related Articles:

• DNA Sequence Completed for Corrosive Bacterium Desulfovibrio vulgaris. The study, funded by DOE, will be published in the May 2004 issue of Nature Biotechnology. [More...]
• "Lawrence Berkeley Laboratories Begins Using Biolog Phenotype MicroArray Technology in Genomes to Life Project," Business Wire, April 27, 2004
• "GENETIC "CODE": Representations and Dynamical Models of Genetic Components and Networks," Annual Reviews Genomics and Human Genetics 2002. 3:341-369.
• "Engineering the Cell," HHMI Bulletin, September 2002, pages 20-23.