Genomic Science Program. Click to return to home page.
Department of Energy Office of Science. Click to visit main DOE SC site.

All Awardee Workshops

Genomics:GTL Contractor—Grantee Workshop IV
and
Metabolic Engineering Working Group Inter-Agency Conference on Metabolic Engineering 2006

North Bethesda, Maryland
February 12-15, 2006

This is the first Genomics:GTL workshop for principal investigators since the release of Genomics:GTL Roadmap: Systems Biology for Energy and Environment in October 2005 (genomicscience.energy.gov). Abstracts and posters for this workshop are organized around the GTL goal and milestones shown below and in the roadmap on pp. 42–55. Many of the research projects are essentially pilots or proof-of-principle studies for systems biology, technology and methods development, computing, and facilities.

Most computing abstracts, instead of comprising a separate category, are associated with appropriate experimental topics. Overarching computing infrastructure and education abstracts are under Milestone 3, GTL Computational Biology Environment.

Abstracts of the Metabolic Engineering Working Group (MEWG), an interagency approach to understanding and using metabolic processes, are identified as such and intermixed with GTL abstracts in relevant program categories.

Genomics:GTL Overarching Scientific Goal

Achieve a predictive, systems-level understanding of biological systems to help enable biobased solutions to DOE mission challenges.

Book PDFs: faster download PDF, 4160 kb; higher resolution PDF, 37,939 kb.

Science and Technology Milestones

Milestone 1: The Code—Understand Gene Structure and Functional Potential of Plants and Microbes and Their Communities

  • Organism Sequencing, Annotation, and Comparative Genomics (PDF, 432 kb)
  • Microbial-Community Sequencing (PDF, 213 kb)
  • Protein Production and Characterization (PDF, 330 kb)
  • Molecular Interactions (PDF, 515 kb)

Milestone 2: The Response—Understand Function, Regulation, and Dynamics in Plants and Microbes and Their Communities

  • Omics: Systems Measurements of Plants, Microbes and Communities (PDF, 1951 kb)
  • Metabolic Network Experimentation and Modeling (PDF, 473 kb)
  • Regulatory Processes (PDF, 351 kb)

Milestone 3: GTL Computational Biology Environment

  • Computing Infrastructure and Education (PDF, 122 kb)

Communication (PDF, 89 kb)

Ethical, Legal, and Societal Issues (PDF, 125 kb)

Table of Contents and Welcome (PDF, 533 kb)

Participants (PDF, 73 kb)

Web Sites (PDF, 65 kb)

Indexes (PDF, 124 kb)

Addendum (PDF, 150 kb)

Printed copies of the abstract book are available to order. Contact us at altonaj@ornl.gov

Now Featuring

FUNDING CALL: Genomic Science: Biosystems Design to Enable Next-Generation Biofuels


Biosystems Design: DRAFT Report from the July 2011 Workshop


  1. News
  2. Reports
  3. Funding
  4. Research

Genomic Science-Related BER Research Highlights

  • Protein Complex Within Plant Cell Wall Associated with Secondary Cell-Wall Synthesis [Nov 30, 2011]
    The plant cell wall polysaccharide pectin is often associated with the tissue softening that occu [more...]
  • Designing Low Lignin, High Biomass Yielding Plants [Nov 28, 2011]
    The major barrier to the efficient conversion of biomass from plant feedstocks to biofuels is bre [more...]
  • Microbial Conversion of Switchgrass to Multiple Drop-In Biofuels [Nov 28, 2011]
    The low efficiency and high cost of enzymes used to break down plant material into sugars remains [more...]
  • How do Microbes Adapt to Diverse Environments? [Nov 22, 2011]
    Earth's microbes live in staggeringly diverse environments, colonizing habitats with extremes of [more...]
  • Permafrost Microbes Could Make Impacts of Arctic Warming Worse [Nov 06, 2011]
    In Earth’s Arctic regions, frozen soils (permafrost) sequester an estimated 1.6 trillion metric t [more...]
  • More BER Research Highlights »